Holding Strong, Healing Naturally™:
Click above to view animation of how TissuGlu Surgical Adhesive* works.

A Revolutionary New Product Line

Strong. Biocompatible. Easy to Use.

Cohera Medical’s novel chemistry has been used to create one-part synthetic adhesives and sealants that cure in the presence of moisture. This means easy application with no mixing or assembly, and no bothersome clogging of the applicator. The adhesives and sealants are resorbable, safe for internal use, and use no human or animal-based ingredients.

Tissues heal naturally

The products are designed to hold tissues together as the natural healing process occurs. After the tissues heal, TissuGlu Surgical Adhesive breaks down into safe components that are then eliminated by the body naturally.

No animal or human ingredients

Cohera Medical’s technology is fully synthetic. These biocompatible adhesives and sealants are composed primarily of lysine, an essential amino-acid, using a chemical design unlike any other products on the market today.

TissuGlu® Surgical Adhesive, the first FDA approved adhesive for internal use, forms a bond between tissue layers that has more than 10x the strength of fibrin-based sealants. By reducing subcutaneous dead space between tissue planes, TissuGlu has been clinically proven to eliminate the need for post-operative drains in most abdominoplasty patients. TissuGlu Surgical Adhesive is indicated for the approximation of tissue layers where subcutaneous deadspace exists between the tissue planes in abdominoplasty.

Sylys® Surgical Sealant is an elastic, resorbable, synthetic sealant designed to help reduce anastomotic leakage in colorectal surgical procedures. Used in conjunction with standard anastomotic closure techniques such as sutures or staples, Sylys protects the suture or staple line, supporting the anastomosis during the first few days of healing when leaks are most likely to occur.

Other products in development: Cohera’s unique chemistry serves as a platform for the development of a range of adhesives and sealants for a variety of indications. These include adhesives designed for mesh fixation, orthopedic applications, and drug delivery.

*Disclaimer: TissuGlu Surgical Adhesive is currently approved for sale in the United States for the approximation of tissue layers where subcutaneous dead space exists between the tissue planes in abdominoplasty. TissuGlu Surgical Adhesive received European CE Mark in 2011, where it is approved for large flap surgical procedures such as abdominoplasty. TissuGlu Surgical Adhesive is not approved for sale in any other region. No other Cohera Medical product is currently approved for sale in any country.

Disclaimer: These products are not currently available for sale or distribution and have not been approved by the U.S. FDA or any other country’s regulatory authority. The devices described are currently limited to non-human investigational use only.