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The Science Behind TissuGlu® Surgical Adhesive
TissuGlu® Surgical Adhesive* is a new, high-strength surgical adhesive that is biocompatible for internal use and designed to help reduce wound drainage while allowing tissues to heal naturally following plastic surgery procedures.
The adhesive begins as a low molecular weight, hyper-branched pre-polymer. Upon application, the ends of the molecules begin adhering to tissue surfaces. The adhesive cures in the presence of moisture with water reacting with the ends of unbounded molecules to bind them together, forming large polymeric chains.
The cured adhesive forms a network of large polymeric chains that allows the adhesive to remain soft and flexible while also creating a strong tissue bond. As tissues continue to heal, hydrolysis eventually degrades the adhesive into harmless, absorbable subcomponents.
TissuGlu Surgical Adhesive requires no mixing and can be stored in the operating room at room temperature. The ergonomic TissuGlu applicator is ready for use with a simple flip of its actuator switch. The applicator’s Multi-Tip™ Pivoting Head delivers measured droplets of the adhesive at the squeeze of its trigger, and the built-in spacer guide aides the surgeon in applying an evenly spaced grid of adhesive to the tissue bed.
By forming a strong bond between tissue planes and reducing dead space in the surgical wound, TissuGlu Surgical Adhesive helps to decrease the amount of post-surgical fluid accumulation and may reduce the length of time drains are required following surgery.1
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Cohera Medical, Inc.® has engaged HealthLink Europe to act as its European Authorized Representative.
- Walgenbach KJ, Bannasch H, Kalthoff S, Rubin JP. Randomized, prospective study of TissuGlu® Surgical Adhesive in the management of wound drainage following abdominoplasty. Aesthetic Plas Surg. 2011 Dec 29. DOI:10.1007/s00266-011-9844-3.
*Disclaimer: TissuGlu Surgical Adhesive received European CE Mark in 2011. Currently, TissuGlu Surgical Adhesive is approved for investigational use only in the United States and is not approved for sale or marketing in the U.S. or any other country outside of the EU. No other Cohera Medical product is currently approved for sale in any country.